23. Massaro, N. P.; Stevens, J. C.; Chatterji, A.; “Stereoselective Synthesis of Diverse Lactones through Diverted Carbene Ketoacid Insertion Reactions 2018 (just submitted)

22. Hunter, A. C.; Chinthapally, K.; Steven, J. C.; Sharma, I. "Studying Baldwin Rules in Enolendo-Exo-Dig Cyclizations for the Stereoselective Synthesis of Spirocarbocycles” 2018 (just submitted).

21. Hunter, A. C.; Almutwalli, B.; Bain, A.; Sharma, I. "Trapping Rhodium Carbenoids with Aminoalkynes for the Synthesis of Diverse N-Heterocycles Tetrahedron 2018 (In Press, Invited article in honor of Derek Barton on his centennial birthday).

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20. Hunter, A.C.; Schlitzer, S.C.; Stevens, J.C.; Almutwalli, B.; Sharma, I. “A Convergent Approach to Diverse Spiroethers through Stereoselective Trapping of Rhodium Carbenoids with Gold Activated Alkynols” J. Org. Chem. 2018, 83, 2744–2752. DOI: 10.1021/acs.joc.7b03196

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19. Chinthapally, K.; Massaro, N.; Padgett, H.L.; Sharma, I. “A Serendipitous Cascade of Rhodium Vinylcarbenoids with Aminochalcones for the Synthesis of Functionalized Quinolines” Chem. Comm. 2017, 53, 12205–12208. DOI: 10.1039/C7CC07181G

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18. Chinthapally, K; Massaro, N. P.; Sharma, I. Rhodium Carbenoid Initiated O–H Insertion/Aldol/Oxy-Cope Cascade for the Stereoselective Synthesis of Functionalized OxacyclesOrg. Lett. 2016, 18, 6340–6343. DOI: 10.1021/acs.orglett.6b03229

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17. Hunter, A. C.; Schlitzer, S. C.; Sharma, I. Synergistic Diazo–OH Insertion/Conia-Ene Cascade Catalysis for the Stereoselective Synthesis of γ-Butyrolactones and tetrahydrofurans” Chem. Eur. J. 2016, 22, 16062–16065 DOI: 10.1002/chem.201603934.

 

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16. In Collaboration with Professor Lakshmi Devi (Mount Sinai, New York) and Joseph Parello (Vanderbilt University); Gupta, A.; Gomes, I.; Bobeck, E. N.; Fakira, A. K.; Massaro, N. P.; Sharma, I.; Cave, A.; Hamm, H. E.; Parello, J.; Devi, L. A. “Collybolide is a Novel Biased Agonist of κ-Opioid Receptors with Potent Antipruritic Activity” Proc. Natl. Acad. Sci. 2016, 113, 6041–6046. DOI: 10.1073/pnas.1521825113

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15. Hunter, A. C.; Chinthapally, K.; Sharma, I. “Rh2(esp)2: An Efficient Catalyst for O–H Insertion Reactions of Carboxylic Acids into Acceptor/Acceptor Diazo Compounds” Eur. J. Org. Chem. 2016, 2260–2263, selected for the front cover page; DOI: 10.1002/ejoc.201600064

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Publications (Prior to Independent Career)

14. Ji, C.; Sharma, I.; Pratihar, D.; Hudson, L. L.; Maura, D.; Guney, T.; Rahme, L. G.; Pesci, E. C.; Coleman, J. P.; Tan, D. S.Designed small-molecule inhibitors of the anthranilyl-CoA synthetase PqsA block quinolone biosynthesis in Pseudomonas aeruginosaACS Chem. Biol. 2016, 11, 3061–3067.

13. Matarlo, J. S.; Evans, E. C.; Sharma, I.; Lavaud, L. J.; Ngo, S. C.; Shek, R.; Rajashankar, K. R.; French, J. B.; Tan, D. S.; Tonge, P. J. “Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents” Biochemistry 2015, 54, 6514–6524.

12. Sharma, I.; Wurst, J.; Tan, D. S. “ Solvent-Dependent Divergent Functions of Sc(OTf)­3 in Stereoselective Epoxide-Opening Spiroketalizations” Org. Lett. 2014, 16, 2474–2477.

11. In collaboration with Dr. Susruta Majumdar (Pasternak Lab, MSKCC), Váradi, A.; Palmer, T. C.; Notis, P. R.; Redel-Traub, G. N.; Afonin, D.; Subrath, J. J.; Pasternak, G. W.; Hu, C.;  Sharma, I.; Majumdar, S.; “Three-Component Coupling Approach for the Synthesis of Diverse Heterocycles Utilizing Reactive Nitrilium Trapping” Org. Lett. 2014, 16, 1668–1671.

10. Sharma, I.; Tan, D. S. News and Views “Drug Discovery Diversifying Complexity” Nature Chemistry 2013, 5, 157–158.

9. Lu, X.; Zhou, R.; Sharma, I.; Li, X.; Kumar, G.; Swaminathan, S.; Tonge, P. J.; Tan, D. S. “Stable Analogues of OSB-AMP: Potent Inhibitors of MenE, the o-Succinylbenzoate-CoA Synthetase from Bacterial Menaquinone Biosynthesis” ChemBioChem. 2012, 13, 129–136.

8. Sharma, I.; Bohe, L.; Crich D. “Influence of Protecting Groups on the Anomeric Equilibrium; Case of the 4,6-O-Benzylidene Acetal in the Mannopyranose Series” Carbohydr. Res. 2012, 357, 126–131.

7. Sharma, I.; Crich D. “Direct Fmoc-Chemistry-Based Solid Phase Synthesis of Peptidyl Thioesters” J. Org. Chem. 2011, 76, 6518–6524.

6. Aubry, S.; Sasaki, K.; Sharma, I.; Crich, D. "Influence of protecting groups on the reactivity and selectivity of glycosylation: Chemistry of the 4,6-O-benzylidene protected mannopyranosyl donors and related species" Topics Curr. Chem. 2011, 301, 141–188.

5. Crich, D.; Sharma, I. “Influence of the O3 Protecting Group on Stereoselectivity in the Preparation of C-Mannopyranosides with 4,6-O-Benzylidene Protected Donors” J. Org. Chem. 2010, 75, 8383–8391.

4. Crich, D.; Sharma, I.Triblock Peptide and Peptide Thioester Synthesis with Reactivity-Differentiated Sulfonamides and Peptidyl ThioacidsAngew. Chem. Int. Ed. 2009, 48, 7591–7594.

3. Crich, D.; Sharma, I. "Epimerization-Free Block Synthesis of Peptides from Thioacids and Amines with Sanger’s and Mukaiyama’s Reagents” Angew. Chem. Int. Ed. 2009, 48, 2355–2358.

2. Crich, D.; Sharma, I. “Is Donor-Acceptor Hydrogen Bonding Necessary for 4,6-O-Benzylidene Directed β-Mannopyranosylation. Stereoselective Synthesis of β-C-Mannopyranosides and α-C-Glucopyaronosides” Org. Lett. 2008, 10, 4731–4734.

1. Mal, D.; Ray, S.; Sharma, I. "Direct Access to 1,4-Dihydroxyanthraquinones: The Hauser Annulation Reexamined with p-Quinones” J. Org. Chem. 2007, 72, 4981–4984.